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Filtered Search Results
Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.
- Selective PROTAC PTPN2 degrader
- Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
- Promotes T cell activation
- Amplifies IFN-γ-mediated anticancer activity
- Composed of a PTPN2 ligand, a linker, and a VHL ligand
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Medchemexpress LLC LM11A-31 25mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 25 MG
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LM11A-31 a non-peptide p75NTR (neurotrophin receptor p75) modulator is an orally active and potent proNGF (nerve growth factor) antagonist LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer s disease mouse models with mid- to late-stage disease progression[1][2]
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Medchemexpress LLC Pomalidomide-amido-c5-peg2-c6-chlorine | 1835705-69-5 | 98.75% | 594.10 | 25 MG
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Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivative of Pomalidomide. It is intended for research use only and is not sold to patients. The compound has a molecular weight of 594.10 and a chemical formula of C29H40ClN3O8. It appears as a white to off-white solid. This compound is cited in research related to the modular design of PROTACs for the degradation of oncogenic BCR-ABL.
- It is a derivative of Pomalidomide.
- It is used for research purposes only.
- It is a solid with a white to off-white appearance.
- It has been utilized in studies concerning PROTAC design for degrading oncogenic BCR-ABL.
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Ambeed 1Methylpyrrolidine
1-Methylpyrrolidine, 120-94-5, 95%
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Apexbio Technology LLC IAA-94 54197-31-8 5mg
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IAA-94 (CAS 54197-31-8) is a small-molecule inhibitor of epithelial chloride channels modulating cellular electrophysiological properties by disrupting chloride ion transport Experimental studies have demonstrated that IAA-94 can interfere with interactions involving the negative factor (Nef) protein during infection indicating its capacity to modulate Nef-mediated processes Due to its specificity in targeting chloride channels IAA-94 is widely utilized in investigations of ion channel-related signaling pathways in tumor cells and serves as a valuable tool in studies of cell electrophysiology and infection mechanisms
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TARGETMOL CHEMICALS INC 6-GNTI DIHYDROCHLORIDE 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. 6'-GNTI dihydrochloride is a (kappa)-opioid receptor (KOR) agonist that favors activation of G-protein-mediated signaling over recruitment of (beta)-aspirin 2. 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons. purity: 98%
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Ambeed 2S 5R 5 6Amino9Hpurin9yl tet
((2S,5R)-5-(6-Amino-9H-purin-9-yl)tetrahydrofuran-2-yl)methanol, 4097-22-7, 98%
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Ambeed 3Chloro4methoxybenzaldehyde
3-Chloro-4-methoxybenzaldehyde, 4903-09-7, 98%
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Ambeed 1 Benzyloxy 4iodo1Hpyrazole
1-(Benzyloxy)-4-iodo-1H-pyrazole, 229171-07-7, 95%
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eMolecules 7-Bromo-1-methyl-1H-quinoxalin-2-one | 82019-32-7 | MFCD10000855 | 250mg
Ambeed | 7-Bromo-1-methyl-1H-quinoxalin-2-one | 250mg | 600833751 | A206593 | | 82019-32-7 | MFCD10000855 | 239.072 | C9H7BrN2O
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Medchemexpress LLC RGW-611 50mg | 6497-78-5 | 50MG
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RGW 611 is a morpholine derivative that enhances radiation-induced cell death of hypoxic V79-379A cells RGW 611 also stimulates fatty acid synthesis[1 [2
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Ambeed Methanesulfonato 2dicyclohexyl
Methanesulfonato(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II), 1599466-83-7, 98+%
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Apexbio Technology LLC SKA 31 40172-65-4 100mg
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SKA 31 (CAS 40172-65-4) is a small-molecule activator of calcium-activated potassium channels selectively targeting KCa3 1 KCa2 2 KCa2 1 and KCa2 3 subtypes It exhibits EC50 values of 260 nM for KCa3 1 1 9 M for KCa2 2 and 2 9 M for both KCa2 1 and KCa2 3 By facilitating the activation of these channels SKA 31 enhances endothelium-derived hyperpolarizing factor (EDHF) responses This compound is employed to investigate endothelial function and signal transduction with notable utility in studies exploring blood pressure regulation and related vascular mechanisms
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Medchemexpress LLC 31-Norlanostenol | 16910-39-7 | 5 MG
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31-Norlanostenol is a triterpenic compound isolated from the latex of *Euphorbia officinarum*. It can act as an efficient insect growth regulator on *S. frugiperda* and *Tenebrio molitor*.
- Triterpenic compound
- Isolated from the latex of *Euphorbia officinarum*
- Acts as an efficient insect growth regulator on *S. frugiperda* and *Tenebrio molitor*
- White to off-white solid
- Molecular weight: 414.71
- Formula: C29H50O
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Ambeed 2Bromo4 6dimethylaniline
2-Bromo-4,6-dimethylaniline, 41825-73-4, 98+%
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